Hugh I know what you are feeling when you have a lack of air but there are a whole slew of things that make you feel like no air. Breathing CO2 or NOx will make you feel like you can't get air. NOx is what triggers ahsama (sp?) attack, the irritants get into those little sacks in your lungs. Breathing CO long enough is different, it takes awhile as it saturates your blood so you can't carry oxygen. CO2 will make your body breathe faster to get more air. Unburned fuel is another irritant but I don't know what its effects are on people. On a grand scale, soot, unburned fuel and NOx are what cause huge smog clouds to hang over areas and cause breathing problems. Engines with high compression and no emissions controls produce lots of NOx. No way around it mechanically speaking without reducing the peak temps in the engine which reduces the power output so you may as well of had lower compression to start with. We have made progress, we squeeze many percent more energy out of each drop of gas than we did back then with our engines all while reducing our emissions. Any losses in mileage are from the trend of uppowering cars. Look at our 0-60 times in the last 50 years. Family sedans now have 240 hp engines and would knock the early supercars on their butts. Another thing to consider is a typical car is now driven to 200k km with out issue, it may have what 3-4 major tunes up in that time? Rarely does the gas mileage change more than a few percent. My old carb'd no anything fancy truck can go from 28 mpg to 17 mpg between oil changes if the carb gets upset and the plugs get a bit fouled.
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