Remember, read the label and follow it, it's the law. don't 'just' go by what you read here.
There are at least 2 common types of glyposate, 4 lb and 6 lb. One is stronger than the other, so know what you are buying and follow the label... (I believe I've head of a 5lb as well???)
For 4 lb, you plant roudup ready crops, wait for the weeds to grow, and spray them. Glyphosate only kills greemn plants that it gets sprayed onto the green parts in good weather. It has _no_ effect on seeds in the ground, etc. The very next day new weeds will be sprouting and start to grow.
Typically glysophate prefers less water per acre than other types of spray, you would mix up about 10 gallons of water and around 32 oz of glyphosate to spray per acre. See what your sprayer puts out, and adjust so you get about that much glyphosate per acre. Sometimes for tough weeds you would want more; sometimes with tank mixes or for other reasons you might want only 1/2 that much.
It is very very very common to add a few lbs of a special nitrogen fertilizer (typically granular, tho a lot of liquid type has been developed now too) which basically softens hard water - glyphosate tends to bind up with hard water and will not be so effective without this.
It is possible to buy glyphosate with or without additives that help it stick to plants and break in through the waxy leaves. Depending on what your label says for the product you buy, you may need or want to add some of his.
That is the very basics. There are a zillion different 'brands' of the stuff, and so hard to say what you should or will buy. For farm use it typically comes in 2.5 gallon jugs, 30 gallon barrels, 250 gallon totes, or you can buy in bulk and need to bring your own approved container to pick it up in. Most of us have good results with generic, imported, or brand name stuff, all seems to work the same anyhow for most of us - the only difference is the strength (lbs of active ingredient) and additives (the sticky/ wax cutting stuff) included in what you buy.
Do look at the label and dirctions of your product for exact requirements and mixes for the crop and weeds and weed size you are dealing with.
Will you be planning on spraying anything else before or with the glyphosate? Will you plan on doing 2 sprays of glyphosate? Especially in the south, but up here in the north too, a few species of weeds have developd resistance to glyphosate and you might need stronger mix to deal with them, or better idea use a scond, different herbicide to deal with them. Any of this can change the amount you ned to use. It is rare for just one spray of glyphosate to take care of the weeds for the whole year; spray early & you will get a second flush of weeds. Spray late and the weeds are large & hurting your crop already....
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